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Hair and cancer


Chemo Hair Loss

Persistent Hair Issues

Hormonal Therapies



Chemotherapy hair loss


Chemotherapy drugs attack rapidly growing cancer cells.
As a drawback, chemotherapy also attacks other rapidly growing cells, such as hair follicle cells, hence causing hair loss.
Hair loss intensity depends on the chemotherapy regimen administered. The following chemotherapy treatments are known for causing varying degrees of hair loss (1).



Agents that usually
cause hair loss
Agents that sometimes
cause hair loss
Agents that rarely
cause hair loss
hairloss_treatment
hairloss_treatment
hairloss_treatment
Adriamycin
Amsacrine
Carboplatin
hairloss_treatment
hairloss_treatment
hairloss_treatment
Cyclophosphamide
Bleomycin
Capecitabine
hairloss_treatment
hairloss_treatment
hairloss_treatment
Daunorubicin
Busulphan
Carmustine
hairloss_treatment
hairloss_treatment
hairloss_treatment
Docetaxel
Cytarabine
Cisplatin
hairloss_treatment
hairloss_treatment
hairloss_treatment
Epirubicin
5-Fluorouracil
Fludarabine
hairloss_treatment
hairloss_treatment
hairloss_treatment
Etoposide
Gemcitabine
Methotrexate
hairloss_treatment
hairloss_treatment
hairloss_treatment
Ifosphamide
Lomustine
Mitomycin C
hairloss_treatment
hairloss_treatment
hairloss_treatment
Irinotecan
Melphalan
Mitroxantrone
hairloss_treatment
hairloss_treatment
hairloss_treatment
Paclitaxel
Thiotepa
Procarbazine
hairloss_treatment
hairloss_treatment
hairloss_treatment
Topotecan
Vinblastine
Raltritrexate
hairloss_treatment
hairloss_treatment
hairloss_treatment
Vindesine
Vincristine
6-Marcaptopurine
hairloss_treatment hairloss_treatment hairloss_treatment
Vinorelbine
Streptozotocin



Hair loss typically starts 1 to 3 weeks after chemotherapy begins.
Hair could fall out very quickly or gradually and your scalp may feel tender.
Hair loss will continue throughout the chemotherapy treatment until baldness, eventually.
The baldness period (between the moment maximum baldness is reached and first hair regrowth) is 20 weeks on average (4).
Duration from start of chemotherapy treatment until maximum hair recovery is on average 6 months (187 days) (4).
New hair texture and color may temporally be different from the hair you lost (1,2).
The pictures below represent the visual progression of hair pattern and macro pictures of the scalp, through and after chemotherapy (3).

The typical course of hair loss, as shown in a patient in group C (chemotherapy), demonstrated by (a) global photography, (b) phototrichogram in the frontal area and (c) phototrichogram in the occipital area.
Left to right, weeks 0, 3, 6, 18 and 28.



Week 0
CG428 Chemoterapy Hair loss

Week 3
CG428 Chemoterapy Hair loss

Week 6
CG428 Chemoterapy Hair loss

Week 18
CG428 Chemoterapy Hair loss

Week 28
CG428 Chemoterapy Hair loss

Source of data: 3.V. Kanti et al. Analysis of quantitative changes in hair growth during treatment with chemotherapy or
tamoxifen in patients with breast cancer: a cohort study - British Journal of Dermatology (2014) 170, pp643–650




hairloss_treatment

hairloss_treatment

hairloss_treatment



Persistent hair issues resulting from chemotherapy


CG428 Chemoterapy Hair lossMore than 70% of patients who had breast cancer adjuvant chemotherapy with FEC > Docetaxel treatment suffer from hair loss even more than two years after the treatment.CG428 Chemoterapy Hair loss Dr. Ito, Hitachi Sogo Hospital - Breast Cancer Society of Japan - 2013

CG428 Chemoterapy Hair loss In a survey conducted 32 months after chemotherapy (median value), 50 patients (53%) responded that hair volume decreased, and 63 patients (74%) responded that hair became thinner.CG428 Chemoterapy Hair loss Dr. Watarai - Breast cancer society of Japan – 2010

Chemotherapy drugs cause “dystrophic anagen” (damage to hairs in the growing phase) and “dystrophic catagen” (damage to transition phase hairs). Dystrophic anagen hair follicles actually recover much more slowly than dystrophic catagen hair follicles (5).
Since generally 80% (6) of hair are in the growing phase (anagen phase), the hair regrowth process after chemotherapy hair loss may be a longer, resulting in persistent hair thinning and decreased hair volume.



hairloss_treatment

hairloss_treatment

hairloss_treatment



Hormonal therapy hair issues


Hormonal therapy is used to treat breast cancers that are sensitive to hormones. It is intended to help reducing the risk of the breast cancer coming back after surgery, and also to treat cancer that has come back after treatment or has spread (10).
Tamoxifen (Nolvadex, Soltamox) causes hair thinning in aproximately 15% of the cases (7, 8).
Estrogen level reducers like aromatase inhibitors (anastrozole - Arimidex, exemestane - Aromasin, letrozole - Femara) can cause hair thinning in 32,6% of the cases (9).


References

(1) Chemotherapy-induced Hair Loss. Trueb RM. Skin Therapy Lett. 2010 Jul-Aug;15 (7):5
(2) Mayo Clinic. Chemotherapy and hair loss: what to expect during treatment. Available at: www.mayoclinic.org/tests-procedures/chemotherapy/in-depth/hair-loss/art-20046920. Last accessed: September 30, 2014.
(3) Analysis of quantitative changes in hair growth during treatment with chemotherapy or tamoxifen in patients with breast cancer: a cohort study - V. Kanti, R. Nuwayhid, J. Lindner, K. Hillmann, A. Stroux, N. Bangemann, A. Kleine-Tebbe, U. Blume-Peytavi and N. Garcia Bartels - British Journal of Dermatology (2014) 170, pp643–650
(4) A randomized trial of minoxidil in chemotherapy-induced alopecia - Duvic, M et al- Journal of the American Academy of Dermatology - Vol.35, No.1, (July 1996), pp. 74-78
(5) Pathobiology of chemotherapy-induced hair loss - Vladimir A Botchkarev et al. - The Lancet Oncology, Vol 14, Issue 2, February 2013
(6) Indications that topical L-carnitin-L-tartrate promotes human hair growth in vivo - Kerstin Foitzik, Edo Hoting, Ulrike Heinrich, Hagen Tronnier, Ralf Paus - Journal of Dermatological Science (2007) 48, 141-144
(7) Alopecia With Endocrine Therapies in Patients With Cancer - V Saggar, S Wu, M Dickler, M Lacouture - The Oncologist 2013; 18:1126–1134
(8) Breast Cancer.org: Why and How Hair Loss Happens. Available at: www.breastcancer.org/tips/hair_skin_nails/hair_loss. Last accessed: September 30, 2014
(9) Breast cancer action group (2008) Side-effects revisited: women’s experiences with aromatase inhibitors. Zivian M, Salgado B - Available at: www.bcaction.org. (accessed october 3, 2014)
(10) www.cancer.org/cancer/breastcancer/detailedguide/breast-cancer-treating-hormone-therapy

Meet CG428


What is CG428 ?

Chemo_What_Expect

Persistent_Hair_Issues_What_Expect




CG428 is a botanical lotion intended to help hair recovery after chemotherapy hair loss.


A study suggest that the period of baldness, from maximum baldness to first regrowth, which is usually 20 weeks, was reduced by 5 to 16 weeks in subjects using the product (1).


CG428 scientific data were presented at the following scientific conferences *:

2013 - Multinational Association of Supportive Care in Cancer (MASCC)
2013 - American Association for Cancer Research (AACR)
2014 - World Hair Research Congress (WHRC)
2014 - American Academy of Dermatology (AAD)
2014 - Multinational Association of Supportive Care in Cancer (MASCC)
2014 - World Congress on Breast Cancer (SIS)
2014 - Society of Integrative Oncology (SIO)
2014 - Critical Mass - Young Adult Cancer Alliance
2014 - San Antonio Breast Cancer Symposium (December 2014)
2015 - Multinational Association of Supportive Care in Cancer (MASCC)
*Oral presentation and/or poster.

(1) CARA - Assessment of the efficacy of CG428 in the recovery from chemotherapy induced alopecia in women (an open label evaluation), Japan 2013


CG428 contains a novel patented blend comprised of four botanicals ingredients: Citrus, Cocoa , Guarana, Onion.
Legacy Healthcare has developed previously CG210, a product for male and female hair loss (not caused by cancer treatments).
CG210 is commercialized by Abbott, Galderma, Sanofi and other healthcare companies.
For more information on where to find CG210, visit www.legacyhealthcare.ch
Legacy Healthcare is a research company based in Switzerland.



How CG428 works?


CG428 helps reestablishing the natural balance of the hair cycle when disturbed by chemotherapy and hormonal cancer treatments.
CG428 helps restoring the optimal environment required for healthy hair growth.
Apart from rare cases of permanent alopecia as a result of chemotherapy, hair should naturally grow back after chemotherapy hair loss. CG428 lotion gives hair a helping hand during this process through restoring a healthy natural hair cycle.


Is CG428 safe?


No side effects and no drug interactions were reported from CG428 use.
In studies, CG428 was found to be safe and well tolerated.
CG428 is hypoallergenic, paraben free and contains non-denatured alcohol.
CG428 contains 4 botanical ingredients.


Precautions
Not to be used by subjects already receiving a treatment on the scalp and head area (eg: head and neck radiotherapy, brain radiotherapy).
Do not apply on altered skin such as open wounds, pustules and skin cancer.
Avoid the use of CG428 in case of any hypersensitivity to one of the components.
For external use only. Avoid contact with eyes. Keep out of reach of children. Do not swallow.


How to use CG428?


Apply CG428 every morning and evening. One bottle should last one month.



CG428 Chemoterapy Hair loss
1 .
Clip the applicator on the bottle. Shake the bottle before each use.
CG428 Chemoterapy Hair loss
2 .
Spray 5 to 10 times onto the entire scalp, with the applicator in contact with your skin.
CG428 Chemoterapy Hair loss
3 .
Massage your scalp delicately with fingertips. Do not wash immediately after application.






CG428 Chemoterapy Hair loss






What is CG428 ?

Chemo_What_Expect

Persistent_Hair_Issues_What_Expect




Hair recovery after chemotherapy hair loss


The fact: On average, first hair regrowth is expected at week 10 after end of chemotherapy treatment (1).
The CARA study suggests that the period of baldness was reduced by 5 - 16 weeks in subjects using the product (2).
In most volunteers, hair was visible over the whole scalp before week 10 after end of chemotherapy.
Reference data (1) mention that only a first hair regrowth is usually observed by week 10.
The pictures aside show that volunteers who have started product application soon after chemotherapy initiation never reached total baldness.

The pictures below show how CG428 benefited cancer patients under chemotherapy in comparaison to the typical course of hair loss.


Typical course of hair loss - without CG428

Reference
Chemo
treatment
Start of
product
use
Before
start of
chemo
(or else)
During
chemo
Week 0
= End of
chemo
Week 2
Week 3
Week 5
Week 6
Week 8
Week 10
Week 12
Week 14
Week 16
V. Kanti
et al. (3)
Cyclophosphamide Taxane
CG428 Chemoterapy Hair loss
End of chemo (week 16 after start of chemo)
CG428 Chemoterapy Hair loss
CG428 Chemoterapy Hair loss
Duvic
et al. (1)
Maximum
hair loss
is reached
usually 6
weeks after
start of chemo
hairloss_treatment
Total balding period from maximum hair loss to first regrowth = 20 weeks
First hair
regrowth



CG428 users - CARA study*

CG428
user
Chemo
treatment
Start of
product
use
Before
start of
chemo
(or else)
During
chemo
Week 0
= End of
chemo
Week 2
Week 3
Week 5
Week 6
Week 8
Week 10
Week 12
Week 14
Week 16
CARA 03
Gemcitabine
Docetaxel
-14 weeks
before
start of
chemo
CG428 Chemoterapy Hair loss
CG428 Chemoterapy Hair loss
CG428 Chemoterapy Hair loss
CG428 Chemoterapy Hair loss
CG428 Chemoterapy Hair loss
CG428 Chemoterapy Hair loss
CARA 04
Docetaxel
Pertuzumab
Trastuzumab
T-DM1
At start
of chemo
CG428 Chemoterapy Hair loss
End of
chemo
CG428 Chemoterapy Hair loss
CG428 Chemoterapy Hair loss
CG428 Chemoterapy Hair loss
CARA 02
Fluorouracil
Epirubicine
Cyclophosphamide
Paclitaxel
At start
of chemo
CG428 Chemoterapy Hair loss
CG428 Chemoterapy Hair loss
End of
chemo
(estimated)
CG428 Chemoterapy Hair loss
CG428 Chemoterapy Hair loss
CG428 Chemoterapy Hair loss
CARA 01
Cyclophosphamide
Doxorubicin
(Adriamycin)
Vincristine
1 week
after start
of chemo
CG428 Chemoterapy Hair loss
CG428 Chemoterapy Hair loss
End of
chemo
CG428 Chemoterapy Hair loss
CG428 Chemoterapy Hair loss
CG428 Chemoterapy Hair loss
CG428 Chemoterapy Hair loss
CARA 05
Cyclophosphamide
Docetacel
Week 2
hairloss_treatment
hairloss_treatment
End of
chemo
hairloss_treatment
hairloss_treatment
hairloss_treatment
hairloss_treatment
CARA 10
Fluorouracil
Epirubicine
Cyclophosphamide
Paclitaxel
2 weeks
before end
of chemo
hairloss_treatment
End of
chemo
hairloss_treatment
hairloss_treatment

The analysis of the results (pictures) was performed by Legacy Healthcare.
The above pictures represent individual cases. Results may vary between individuals.



References

* Data on file
(1) A randomized trial of minoxidil in chemotherapy-induced alopecia - Duvic, M et al- Journal of the American Academy of Dermatology - Vol.35, No.1, (July 1996), pp. 74-78
(2) CARA - Assessment of the efficacy of CG428 in the recovery from chemotherapy induced alopecia in women (an open label evaluation), Japan 2013
(3) Analysis of quantitative changes in hair growth during treatment with chemotherapy or tamoxifen in patients with breast cancer: a cohort study - V. Kanti, R. Nuwayhid, J. Lindner, K. Hillmann, A. Stroux, N. Bangemann, A. Kleine-Tebbe, U. Blume-Peytavi and N. Garcia Bartels - British Journal of Dermatology (2014) 170, pp643–650





What is CG428 ?

Chemo_What_Expect

Persistent_Hair_Issues_What_Expect




Persistent hair issues resulting from chemotherapy


The fact: 70% of women who had breast cancer adjuvant chemotherapy treatment still complain from persistent hair issues, such as thinning hair, even more than two years after the treatment (1).

After 3 months of CG428 application, improvement was observed and reported* by 76,2% of volunteers (2).
First improvements were observed and reported as early as 1 month in 33,3 % of the volunteers.
14,3 % of volunteers have not yet observed any improvement after 4 months of application.


Case selection from RELAC study on CG428 efficacy*

Years since end
of chemotherapy
Hair issues reported by volunteers
Start of
CG428
Month 1
Month 2
Month 3
First improvement
reported after
2.4 years
Hair never normalized:
Lower volume and thinner hair
compared to before chemotherapy.
hairloss_treatment
hairloss_treatment
hairloss_treatment
hairloss_treatment
1 month of
CG428 application
4.6 years
Hair did not normalize 4 years after
chemotherapy. I have tried several
products without results.
hairloss_treatment
hairloss_treatment
hairloss_treatment
hairloss_treatment
1 month of
CG428 application
12.5 years
More than 12 years after end of
chemotherapy, frontal area never
fully recovered.
hairloss_treatment
hairloss_treatment
hairloss_treatment
hairloss_treatment
1 month of
CG428 application
1.5 year
19 months after end of
chemotherapy the back area
didn’t recover properly.
hairloss_treatment
hairloss_treatment
3 months of
CG428 application



References

* Data on file
(1) Breast Cancer Society of Japan Annual Meeting, 2013 - Dr Ito, Sogo Hitachi Hospital
(2) RELAC - Assessment of the efficacy of CG428 in the recovery from chemotherapy long term side effects on hair in women (an open label evaluation), Japan 2013

Where do you stand?

CG428 Chemoterapy Hair loss

I did not start or just started my cancer treatment.

You may experience hair loss after the second chemotherapy session. CG428 users who started product application at this stage reported the quickest hair recovery among CG428 users.
CG428 Chemoterapy Hair loss

I am currently experiencing chemotherapy hair loss.

CG428 users who started product application during chemotherapy tend to report satisfactory hair recovery after completing chemotherapy treatment.


CG428 Chemoterapy Hair loss

I have now completed my chemotherapy treatment.

You are on your way to hair recovery. CG428 users who started product application after completing their cancer treatment have reported early beneficial effect on the appearance of their hair.
CG428 Chemoterapy Hair loss

I had chemo long ago but
I am still unhappy with my hair.


For users complaining from hair thinning, chronic hair loss, and reduced hair volume several years after chemotherapy treatment, CG428 application resulted in improved hair volume and appearance after 2 to 3 months of use.


Apart from rare cases of permanent alopecia as a result of chemotherapy, hair should naturally grow back after chemotherapy hair loss. CG428 lotion gives hair a helping hand during this process through restoring a healthy natural hair cycle. This document contains information related to chemotherapy induced alopecia. Such information is provided for educational purposes only, does not constitute medical advice, and is not meant to be a substitute for the advice of your oncologist or other healthcare professional.
In the studies performed by Legacy Healthcare to assess the efficacy of CG428, volunteers were asked to provide a feedback on their personal experience with the product.
The testimonials below were translated from Japanese to English.




chemotherapy hair loss
Woman, age 42
Diagnosed with malignant lymphoma
Chemotherapy treatment: Cyclophosphamide, Adriamycin, Vincristine
Started CG428 one week after beginning of chemotherapy treatment.
_____________________________________________________________________________


My Story

chemotherapy hair lossAs expected I lost a lot of hair during my chemotherapy, but the remaining hair I had was still growing during the treatment, which made me confident. 2 months after the end of chemotherapy, I was already observing many new growing hair. I was glad to see hairs regrow at sides too. At 3 months my parents were really suprised to see my improvement since the previous month ; it was really encouraging to see their reaction. After shampooing my top scalp hair were upright and looked healthy. I really felt confident to go out without a wig or cap after 6 months. At that time I had the equivalent of a very short hair style and I felt relieved.chemotherapy hair loss

My pictures

chemotherapy hair loss

During
Chemotherapy
chemotherapy hair loss

3 months
after chemotherapy
chemotherapy hair loss

4 months
after chemotherapy
chemotherapy hair loss

6 months
after chemotherapy





chemotherapy hair loss
Woman, age 38
Diagnosed with uterine sarcoma
Chemotherapy treatment: Gemcitabine, Docetaxel
Started CG428 before the beginning of chemotherapy treatment.
_____________________________________________________________________________


My Story

chemotherapy hair lossI have started the product before my chemotherapy. I lost most of my hair during the treatment but at my 9th chemotherapy session, I noticed some hair starting to growth. During the 4 next chemotherapy sessions, my hair kept growing. At that time, when I looked at the mirror every morning, I felt my hair was growing each day. The hair at the hairline and the sides seemed to be growing the most. This may be because I apply the lotion from this area. 3 months after my last chemotherapy session I had enough hair to stop using my partial wig and I was able to return to work.chemotherapy hair loss

My pictures

chemotherapy hair loss

9th chemothe-
rapy session
chemotherapy hair loss

End of chemothe-
rapy (13th session)
chemotherapy hair loss

3 months
after chemotherapy





chemotherapy hair loss
Woman, age 47
Never fully recovered her hair after chemotherapy treatment against breast cancer.
4.5 years after her last chemotherapy session, she started CG428.
_____________________________________________________________________________


My Story

chemotherapy hair lossEven 4 years after cancer, my hair never really came back, especially on the frontal area. I have tried several products that weren’t really efficient and I usually gave up after 1 year. But this time I feel the product is working. After 1 month I could already see a little hair growth. I have been using the product for 2 months already. I look forward to keep improving.chemotherapy hair loss

My pictures

chemotherapy hair loss

Started CG428,
4 years after last
chemotherapy
chemotherapy hair loss

1 month from
CG428 start
chemotherapy hair loss

2 months from
CG428 start





chemotherapy hair loss
Woman, age 66
Never fully recovered her hair after chemotherapy treatment against breast cancer.
12.6 years after her last chemotherapy session, she started CG428.
_____________________________________________________________________________


My Story

chemotherapy hair lossMore than 12 years after my cancer treatment, my hair didn’t regrow on the frontal area.
After 1 month of use, I feel the improvement since less hair is falling. At 2 months, there is still not much volume, but the hair itself is thicker and stronger and I see new hair on the frontal area. I would like to keep on using the product.chemotherapy hair loss

My pictures

chemotherapy hair loss

Started CG428,
12 years after last
chemotherapy
chemotherapy hair loss

1 month from
CG428 start
chemotherapy hair loss

2 months from
CG428 start

_____________________________________________________________________________

Share


Your experience can help others.
Please share your story.


yourstory@cg428.com

hairloss_treatment

Questions & Answers


Q. Will I recover my hair after chemotherapy hair loss?
A. Apart from rare cases of permanent alopecia as a result of chemotherapy, hair should naturally grow back after chemotherapy hair loss. CG428 lotion gives hair a helping hand during this process through restoring a healthy natural hair cycle.

Q. Is CG428 efficient?
A. Efficacy of CG428 was assessed through 2 studies. You will find more information on What to expect? section.

Q. What does CG428 contain?
A. CG428 contains a novel patented blend comprised of four botanicals ingredients: Citrus, Cocoa , Guarana, Onion. It also contains water, non-denatured alcohol, fragrance and excipients.

Q. Is CG428 safe?
A. In studies, CG428 was found to be safe and well tolerated. CG428 is hypoallergenic, paraben free.

Q. Will CG428 interact with my chemotherapy treatment?
A. CG428 is a cosmetic lotion. No side effects and no drug interactions were reported from CG428 use.

Q. At which stage of my chemotherapy treatment should I use CG428: before, during or after?
A. You can use CG428 at every stage. You will find more information on Where do you stand? section.

Q. Will CG428 be more effective if I start using it before, during or after my chemotherapy treatment?
A. Based on CARA study results, CG428 users who started product application the earliest reported the quickest hair recovery. Results may vary between individuals and chemotherapy treatments.

Q. Will I lose my hair during chemotherapy and why?
A. On average 65% of chemotherapy patients will experience some degree of hair loss. Chemotherapy drugs attack rapidly growing cancer cells. As a drawback, chemotherapy treatments also attack other rapidly growing cells such as hair follicle cells. (1)

Q. Which chemotherapy treatments cause hair loss?
A. The following chemotherapy treatments are known for causing some degree of hair loss (1) :



Agents that usually
cause hair loss
Agents that sometimes
cause hair loss
Agents that rarely
cause hair loss
hairloss_treatment
hairloss_treatment
hairloss_treatment
Adriamycin
Amsacrine
Carboplatin
hairloss_treatment
hairloss_treatment
hairloss_treatment
Cyclophosphamide
Bleomycin
Capecitabine
hairloss_treatment
hairloss_treatment
hairloss_treatment
Daunorubicin
Busulphan
Carmustine
hairloss_treatment
hairloss_treatment
hairloss_treatment
Docetaxel
Cytarabine
Cisplatin
hairloss_treatment
hairloss_treatment
hairloss_treatment
Epirubicin
5-Fluorouracil
Fludarabine
hairloss_treatment
hairloss_treatment
hairloss_treatment
Etoposide
Gemcitabine
Methotrexate
hairloss_treatment
hairloss_treatment
hairloss_treatment
Ifosphamide
Lomustine
Mitomycin C
hairloss_treatment
hairloss_treatment
hairloss_treatment
Irinotecan
Melphalan
Mitroxantrone
hairloss_treatment
hairloss_treatment
hairloss_treatment
Paclitaxel
Thiotepa
Procarbazine
hairloss_treatment
hairloss_treatment
hairloss_treatment
Topotecan
Vinblastine
Raltritrexate
hairloss_treatment
hairloss_treatment
hairloss_treatment
Vindesine
Vincristine
6-Marcaptopurine
hairloss_treatment hairloss_treatment hairloss_treatment
Vinorelbine
Streptozotocin



Q. Does tamoxifen provoke hair loss?
A. Tamoxifen, a hormonal therapy for breast cancer, is known for inducing hair disorders such as hair thinning and chronic hair loss. (2)

Q. How fast will I lose my hair?
A. On average hair usually begins falling out one to three weeks after the start of chemotherapy. It could fall out quickly or gradually (1).

Q. Will I become completely bald?
A. There is no straightforward answer. The degree of hair loss varies between patients, chemotherapy drugs and doses.

Q. Can I prevent my hair from falling?
A. Cold cap and cooling cap devices are intended to prevent hair from falling during chemotherapy. Their efficacy is variable.
More information is available on www.mayoclinic.org

Q. How long does it take for my hair to grow back after chemotherapy hair loss?
A. Studies indicate that hair is back to its pre-treatment aspect after 6 to 12 months.
More information is available on www.cancer.net

Q. Will my hair grow differently?
A. Change in hair texture and color occurs in 60% of patients (3).



References

(1) Chemotherapy-Induced Alopecia - Ralph M. Trüeb - Department of Dermatology, University Hospital of Zurich - Semin Cutan Med Surg 28:11-14, 2009
(2) Alopecia With Endocrine Therapies in Patients With Cancer - V Saggar, S Wu, M Dickler, M Lacouture - The Oncologist 2013; 18:1126–1134
(3) Pathobiology of chemotherapy-induced hair loss - Vladimir A Botchkarev et al - The Lancet Oncology, Vol 14, Issue 2, February 2013

About you and us


About_us

Access Program



About us


Legacy Healthcare is a research company based in Switzerland.
Our goal is to improve the quality of life of people suffering from skin and hair disorders, and cancer treatments side effects.

We look into nature to find botanical alternatives and put them through our research to develop safe and effective solutions.
To date, we have developed two products: CG210 and CG428.

CG210 is a breakthrough topical botanical hair lotion for female and male hair loss (not related to cancer treatments).
CG210 is commercialized by Abbott, Galderma, Sanofi and other healthcare companies.

Our research work was published and presented at major scientific congresses worldwide*.


Supportive oncology
Dermatology
hairloss_treatment
hairloss_treatment
SABCS - San Antonio Breast Cancer Symposium - 2014 - USA
Singapore International Conference on Skin Research - 2014 - Singapore
hairloss_treatment
hairloss_treatment
Critical Mass - Young Adult Cancer Alliance - 2014 - USA
AAD - American Academy of Dermatology - 2014 - USA
hairloss_treatment
hairloss_treatment
SIO - Society of Integrative Oncology - 2014 - USA
EADV - European Academy of Dermatology & Venereology - 2014 - Serbia
hairloss_treatment
hairloss_treatment
SIS - World Congress on Breast Cancer - 2014 - USA
WCHR - World Congress for Hair Research - 2014 - Korea
hairloss_treatment
hairloss_treatment
AACR - American Association for Cancer Research - 2014 - USA
EADV - European Academy of Dermatology & Venereology - 2013 - Turkey
hairloss_treatment
hairloss_treatment
MASCC - Multinational Association for Supportive Care in Cancer - 2014- USA
WCHR - World Congress for Hair Research - 2013 - Scotland
hairloss_treatment
hairloss_treatment
AACR - American Association for Cancer Research - 2013 - USA
ISHRS - International Society for Hair Restoration Surgery - 2012 - The Bahamas
hairloss_treatment
hairloss_treatment
MASCC - Multinational Association for Supportive Care in Cancer - 2013- USA
JSCHR - Japan Society of Clinical Hair Restoration - 2012 - Japan
hairloss_treatment
hairloss_treatment
MASCC - Multinational Association for Supportive Care in Cancer - 2015 - Denmark
WCD - World Congress of Dermatology - 2015 - Canada
hairloss_treatment
hairloss_treatment
YSC - Young Survival Coalition - 2015 - USA
hairloss_treatment
NCBC - National Consortium of Breast Centers - 2015 - USA
hairloss_treatment
ONS - Oncology Nursing Society - 2015 - USA
hairloss_treatment
* Oral presentation or Poster presentation



Find more information about Legacy Healthcare on www.legacyhealthcare.ch


Switzerland office
Rte de la Corniche 3B
1066 Epalinges (Lausanne)
+41 21 552 21 70
contact@legacyhealthcare.ch


USA office
1 Stults Drive,
Plainsboro, New Jersey 08536
contact.usa@legacyhealthcare.ch


Japan office
TOC Daiichi Bldg. 6F
1-8-3 Shibuya, Shibuya-ku, Tokyo 150-0002
+81 3-6805-0651
contact.jp@legacyhealthcare.ch





About_us

Access Program




CG428's programs


At Legacy, we believe that every woman should benefit from CG428, despite the difficulties they may encounter during their fight against cancer.
Therefore, Legacy Healthcare is dedicated to creating partnership with support groups and making available certain quantity of CG428 for free to individual users.

Community Program
If you are a support group or an advocate, the Community Program allows you to receive CG428 samples corresponding to a certain number of months’ supply to as many as 10 members.
All members of your support group will also benefit from a discount on any purchase of CG428.

Access Program
If you are an individual, not connected to a support group, and you cannot access CG428 because of financial reasons, we will be happy to provide you with 3 month-supply of CG428.
During the Access Program, you can follow the progress of your hair improvement by taking pictures and share it with others. But this is not a requirement to participate.
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chemotherapy hair loss




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